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Biochem Biophys Res Commun. 1992 Jul 31;186(2):918-25.

A homology domain shared between Drosophila optomotor-blind and mouse Brachyury is involved in DNA binding.

Author information

1
Theodor-Boveri-Institut, Lehrstuhl für Genetik, Würzburg, Germany.

Abstract

The distribution of sequence elements divides the optomotor-blind protein into three regions and is suggestive of a transcriptional regulatory role of this protein. The central region of Omb is homologous to the N-terminal half of the Brachyury protein. The conserved domain of Omb is here shown to possess general DNA binding affinity but has no significant similarity to recognized DNA binding motifs.

PMID:
1497674
DOI:
10.1016/0006-291x(92)90833-7
[Indexed for MEDLINE]

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