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Curr Hypertens Rep. 2004 Feb;6(1):66-73.

Metabolic syndrome X: an inflammatory condition?

Author information

1
Reflexis Systems, Inc., 1420 Providence Highway, Suite #266, Norwood, MA 02062, USA. undas@efasciences

Abstract

Obesity, atherosclerosis, insulin resistance and hyperinsulinemia, hyperlipidemia, essential hypertension, type 2 diabetes mellitus, and coronary heart disease (CHD) are the components of metabolic syndrome X and are associated with elevated plasma levels of C-reactive protein, interleukin-6, and tumor necrosis factor-alpha, which are markers of inflammation. This suggests that metabolic syndrome X is a low-grade, systemic, inflammatory condition. Hence, instituting anti-inflammatory measures might be beneficial in preventing or halting the progress of metabolic syndrome X in high-risk populations.

PMID:
14972097
DOI:
10.1007/s11906-004-0014-8
[Indexed for MEDLINE]

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