Format

Send to

Choose Destination
Bull Exp Biol Med. 2003 Nov;136(5):448-50.

Immune system in vasopressin-deficient rats during ontogeny.

Author information

1
Laboratory of Physiological Genetics, Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia. khegay@bionet.nsc.ru.

Abstract

Morphofunctional immune disorders were revealed in vasopressin-deficient Brattleboro rats with diabetes insipidus during ontogeny. We observed a permanent decrease in the number of blood lymphocytes, increase in neutrophil count, reduced activity of macrophages, early involution of the thymus and spleen, and suppression of antibody production. These changes reflect impaired general resistance of these animals.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center