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World J Surg. 2004 Mar;28(3):321-6. Epub 2004 Feb 17.

Aging and wound healing.

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Burn and Shock Trauma Institute, Department of Surgery, Loyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USA.


Impaired wound healing in the elderly presents a major clinical and economic problem. With the aging population growing in both number and percentage, the importance of understanding the mechanisms underlying age-related impairments in healing is increased. Normal skin exhibits characteristic changes with age that have implications for wound healing. Additionally, the process of wound healing is altered in aged individuals. Although historically healing in the aged was considered defective, there is now consensus that healing in the elderly is delayed but the final result is qualitatively similar to that in young subjects.

[Indexed for MEDLINE]

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