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Trends Genet. 1992 Dec;8(12):413-6.

Activation of V(D)J recombination by RAG1 and RAG2.

Author information

1
Department of Molecular Biology, Massachusetts General Hospital, Boston 02114.

Abstract

V(D)J recombination is normally limited to lymphoid cells, but expression of the RAG1 and RAG2 genes allows other cell types to carry out this reaction. The products of these recently discovered genes may form part of the recombination machinery, and are a focal point for lymphoid development.

PMID:
1492366
[Indexed for MEDLINE]

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