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AIDS Res Hum Retroviruses. 1992 Nov;8(11):1863-8.

Association of mycoplasma with HIV-1 and HTLV-I in human T lymphocytes.

Author information

1
Population Council, New York, NY 10021.

Abstract

Recent findings from a number of investigators suggest associations between mycoplasma and HIV or AIDS. We used a quantitative morphometric technique to analyze electron micrographs of human T lymphocytes that were infected with both mycoplasma and/or HIV-1. We observed that lymphocytes which were associated with HIV-1 were much more likely to be associated with mycoplasma than cells that were not (p < .001). Similarly, cells with associated HTLV-I were more likely to be associated with mycoplasma than cells which were not associated with mycoplasma (p < .0001). In addition, mycoplasma and virus were observed in the same region in 90% of cases. These observations suggest that adherence of mycoplasma to lymphocytes that are chronically infected with human retrovirus may trigger viral release.

PMID:
1489576
DOI:
10.1089/aid.1992.8.1863
[Indexed for MEDLINE]

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