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Planta Med. 1992 Dec;58(6):513-5.

Hypoglycemic activity of olive leaf.

Author information

1
Departamento de Farmacologia, Facultad de Farmacia, Universidad de Granada, Spain.

Abstract

The hypoglycemic activity of olive leaf was studied. Maximum hypoglycemic activity was obtained from samples collected in the winter months, especially in February. One of the compounds responsible for this activity was oleuropeoside, which showed activity at a dose of 16 mg/kg. This compound also demonstrated antidiabetic activity in animals with alloxan-induced diabetes. The hypoglycemic activity of this compound may result from two mechanisms: (a) potentiation of glucose-induced insulin release, and (b) increased peripheral uptake of glucose.

PMID:
1484890
DOI:
10.1055/s-2006-961538
[Indexed for MEDLINE]

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