Format

Send to

Choose Destination
Curr Opin Genet Dev. 1992 Dec;2(6):850-6.

Biology and applications of human minisatellite loci.

Author information

1
Department of Genetics, University of Leicester, UK.

Abstract

Highly repetitive minisatellites' include the most variable human loci described to date. They have proved invaluable in a wide variety of genetic analyses, and despite some controversies surrounding their practical implementation, have been extensively adopted in civil and forensic casework. Molecular analysis of internal allelic structure has provided detailed insights into the repeat-unit turnover mechanisms operating in germline mutations, which are ultimately responsible for the extreme variability seen at these loci.

PMID:
1477530
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center