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Am J Cardiol. 2004 Feb 1;93(3):343-6.

Effect of caffeine administered intravenously on intracoronary-administered adenosine-induced coronary hemodynamics in patients with coronary artery disease.

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1
Division of Cardiovascular Disease, Birmingham's Veterans Affair Medical Center, and Department of Medicine, University of Alabama at Birmingham, 35233, USA. raqel@cardio.dom.uab.edu

Abstract

It is believed that caffeine attenuates the coronary hyperemic response to adenosine by blocking the A2a receptors. We studied the effect of caffeine on adenosine-induced myocardial hyperemia measured by fractional flow reserve after intracoronary adenosine administration. Fractional flow reserve was not affected by intravenous caffeine infusion at a dose that was comparable to oral consumption.

PMID:
14759387
DOI:
10.1016/j.amjcard.2003.10.017
[Indexed for MEDLINE]
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