Format

Send to

Choose Destination
J Clin Invest. 2004 Feb;113(3):321-33.

Helicobacter pylori persistence: biology and disease.

Author information

1
Department of Medicine, New York University School of Medicine, and New York Harbor Veterans Affairs Medical Center, New York 10016, USA. martin.blaser@med.nyu.edu

Abstract

Helicobacter pylori are bacteria that have coevolved with humans to be transmitted from person to person and to persistently colonize the stomach. Their population structure is a model for the ecology of the indigenous microbiota. A well-choreographed equilibrium between bacterial effectors and host responses permits microbial persistence and health of the host but confers risk of serious diseases, including peptic ulceration and gastric neoplasia.

PMID:
14755326
PMCID:
PMC324548
DOI:
10.1172/JCI20925
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for American Society for Clinical Investigation Icon for PubMed Central
Loading ...
Support Center