Format

Send to

Choose Destination
See comment in PubMed Commons below
Lancet. 2004 Jan 24;363(9405):291-2.

Synthesis of vitamin D in skin after burns.

Author information

1
Department of Paediatrics, University of Texas Medical Branch, Galveston TX 77555-0352, USA. gklein@utmb.edu

Abstract

Severe burn injury is associated with vitamin D deficiency, low bone turnover, and abnormalities in calcium homoeostasis. Patients do not routinely receive vitamin D supplementation and sun exposure is currently not controlled. By analysis of skin biopsy samples for vitamin D3 precursors after exposure to ultraviolet B light we found that the conversion of 7-dehydrocholesterol to previtamin D3 was reduced in children a mean of 14 months after the burn. Low serum 25-hydroxyvitamin D concentrations were also found. We conclude that vitamin D supplementation is necessary after burn injury.

PMID:
14751703
DOI:
10.1016/S0140-6736(03)15388-3
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center