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Phytother Res. 2004 Jan;18(1):84-6.

Effects of Rhus coriaria L (Anacardiaceae) on lipid peroxidation and free radical scavenging activity.

Author information

1
University of Cumhuriyet, Faculty of Science and Art, Department of Chemistry, Sivas, Turkey. Candan@cumhuriyet.edu.tr

Abstract

In order to evaluate the antioxidant potential of Rhus coriaria L. (Anacardiaceae), a well-known spice, the methanolic extract (water-soluble part) was prepared and investigated using free radical-generating systems in vitro. The IC(50) value of the extract for lipid peroxidation was estimated as 1200 microg/mL in the Fe(+2)-ascorbate system while those for superoxide-scavenging activity in the xanthine-xanthine oxidase method and hydroxyl radical scavenging activity in the deoxyribose decomposition method were 282.92 microg/mL and 3850 microg/mL, respectively. These data suggest that the methanolic extracts of Rhus coriaria L. fruits have considerable antioxidant activity against free radicals and lipid peroxidation in vitro, a fact that may encourage in vivo studies.

PMID:
14750207
DOI:
10.1002/ptr.1228
[Indexed for MEDLINE]
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