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Antimicrob Agents Chemother. 2004 Feb;48(2):648-50.

Emergence in Klebsiella pneumoniae and Enterobacter cloacae clinical isolates of the VIM-4 metallo-beta-lactamase encoded by a conjugative plasmid.

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  • 1Laboratorio di Microbiologia, Ospedale di Circolo, and Universit√† dell'Insubria, I-21100 Varese, Italy.

Abstract

Resistance to carbapenems is an emerging problem among gram-negative hospital pathogens. A transferable plasmid encoding the VIM-4 metallo-beta-lactamase was detected in isolates of Klebsiella pneumoniae and Enterobacter cloacae obtained from a single patient under carbapenem therapy. Thus, enterobacteria appear to increasingly contribute to the spread of VIM-type enzymes.

PMID:
14742229
PMCID:
PMC321512
[PubMed - indexed for MEDLINE]
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