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Microbes Infect. 2004 Jan;6(1):129-39.

Cell biology of the intracellular infection by Legionella pneumophila.

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Department of Microbiology and Immunology, University of Louisville College of Medicine, Louisville, KY 40292, USA.


Legionella pneumophila has become a paradigm for facultative intracellular pathogens that modulate biogenesis of their phagosomes into replicative niches. The ability to alter host cell biology and tailor it into a hospitable host for intracellular proliferation is at the crux of the mechanism of pathogenesis of Legionnaires' disease.

[Indexed for MEDLINE]

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