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Microbes Infect. 2004 Jan;6(1):101-12.

Adhesins and invasins of pathogenic bacteria: a structural view.

Author information

1
Department of Structural Biology, German Research Center for Biotechnology (GBF), Mascheroder Weg 1, 38124, Braunschweig, Germany.

Abstract

Adhesion and invasion of pathogenic bacteria represent the important initial step of infection. Pathogens utilize surface-located adhesins/invasins for specific interaction with host cell receptors. The three-dimensional structures of a number of adhesins/invasins show that many are elongated molecules containing domains commonly found in eukaryotic proteins. Similar folds are employed repeatedly to target different receptors.

PMID:
14738899
DOI:
10.1016/j.micinf.2003.11.001
[Indexed for MEDLINE]

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