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Int J Infect Dis. 2004 Mar;8(2):111-20.

Burden of hospitalization of patients with Candida and Aspergillus infections in Australia.

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1
Infectious Diseases, Peter MacCallum Cancer Institute, East Melbourne, Victoria, Australia.

Abstract

OBJECTIVES:

This study examined the burden of hospitalization of patients with Aspergillus and Candida infections in Australia from 1995 to 1999.

METHODS:

Data were extracted from the National Hospital Morbidity Database. A hospitalization with an aspergillosis diagnosis was defined as any discharge with a diagnosis of aspergillosis. A hospitalization with a candidiasis diagnosis was defined as any discharge with a diagnosis of disseminated, invasive, or non-invasive candidiasis. Outcome measures included number of hospitalizations, length of stay (LOS), cost (AUS$), and mortality.

RESULTS:

4583 hospitalizations with an aspergillosis diagnosis and 57,758 hospitalizations with a candidiasis diagnosis were identified. These hospitalizations were associated with a total of 813,398 hospital days, AUS$563 million in cost, and 4967 in-hospital deaths during the study period. The mean LOS for a hospitalization with an aspergillosis diagnosis was 12 days, cost AUS$9,334, and was associated with 8% mortality. For disseminated, invasive, and non-invasive candidiasis, the respective mean LOS were 31, 17, and 12 days; costs were AUS$33,274, AUS$12,954, and AUS$7,694; and mortality was 26%, 9%, and 8%.

CONCLUSIONS:

Hospitalizations with diagnoses for fungal infections were associated with lengthy hospital stays, high costs, and high mortality.

PMID:
14732329
[Indexed for MEDLINE]
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