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Trends Cell Biol. 1995 Jul;5(7):278-82.

Nuclear migration advances in fungi.

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Dept of Pharmacology, Robert Wood Johnson Medical School, University of Medicine and Dentistry, 675 Hoes Lane, Piscataway, NJ 08854, USA.


Nuclear migration encompasses three areas: separation of daughter nuclei during mitosis, congress of parental nuclei before they fuse during fertilization, and positioning of nuclei in interphase cells. This review deals primarily with interphase nuclear migration, which is crucial for events as disparate as vertebrate embryonic development and growth of fungal mycelia. Mutants of Aspergillus nidulans, Neurospora crassa and Saccharomyces cerevisiae have been particularly informative, and a detailed molecular analysis of this process is now well under way.

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