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Trends Cell Biol. 1994 Jul;4(7):236-40.

Kinesin-like proteins in the flagella of Chlamydomonas.

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Department of Biology, Yale University, PO Box 208103, New Haven, CT 06520-8103, USA.


The flagella of the biflagellate unicellular alga Chlamydomonas have long been known to contain the microtubule-dependent motor protein dynein, but recent findings indicate they also contain multiple members of the kinesin superfamily. Two of these kinesin-like proteins are restricted to a single central-pair microtubule, raising the question of how proteins are targeted to specific microtubules within the flagellum. The kinesin-like proteins on the central-pair microtubules may cause the central-pair apparatus to rotate or twist during flagellar beating. Other kinesins within the flagellum may participate in movements associated with the flagellar membrane.


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