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Trends Cell Biol. 1994 Sep;4(9):305-10.

Ca2+ channels and signalling in cilia and flagella.

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Marine Biological Laboratory, Woods Hole, MA 02543, USA.


Ca(2+) plays a key role in the regulation of ciliary and flagellar movement. This article focuses on the initial steps of this regulation: how and where Ca(2+) enters cilia and flagella to trigger specific changes in axonemal motility. This knowledge is fundamental for understanding the sites, molecular targets and mechanisms of action of Ca(2+) within the cilium of flagellum.


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