Community-acquired methicillin-resistant Staphylococcus aureus skin infections at an outpatient university health center were evaluated. In all, 41 cultures were performed in 36 of 853 patients. Of the 19 patients with S aureus infection, methicillin resistance occurred in 10 (53%) and generally manifested as abscesses or cellulitis. Therefore, methicillin resistance should be considered, even in the community setting, and appropriate cultures performed.