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J Clin Oncol. 2004 Jan 15;22(2):354-60.

Quality of life among disease-free survivors of rectal cancer.

Author information

1
Surgical Department and Medical Oncology, Centre Alexis Vautrin, 54511 Vandoeuvre lès Nancy, France. p.rauch@nancy.fnclcc.fr

Abstract

PURPOSE:

To identify factors affecting the quality of life (QoL) of disease-free survivors of rectal cancer.

PATIENTS AND METHODS:

One hundred twenty-one patients in complete remission more than 2 years after diagnosis were asked to complete three QoL questionnaires: the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30; its colorectal module, QLQ-CR38; and the Duke generic instrument.

RESULTS:

Patients reported less pain (P =.002) than did controls drawn from the general population. EORTC QLQ-C30 physical scores were also higher among rectal cancer survivors than in the general Norwegian or German population (P =.0005 and P =.002, respectively). Unexpectedly, stoma patients reported better social functioning than did nonstoma patients (P =.005), with less anxiety (P =.008) and higher self-esteem (P =.0002). In the present authors' experience, the QLQ-CR38 does not discriminate between these groups. Residual abdominal or pelvic pain and constipation had the most negative influence on QoL.

CONCLUSION:

QoL is high among rectal cancer survivors, including stoma patients. Simultaneous use of several QoL questionnaires appears to have value in follow-up and in monitoring the effects of therapy. The impact of residual pain and constipation on long-term QoL should be considered when establishing a treatment regimen.

PMID:
14722043
DOI:
10.1200/JCO.2004.03.137
[Indexed for MEDLINE]

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