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Arch Gynecol Obstet. 1992;252(2):99-102.

Treatment of lymphangioleiomyomatosis by ovariectomy, interferon alpha 2b and tamoxifen--a case report.

Author information

1
Department of Gynecology and Obstetrics, Hanusch-Krankenhaus, Vienna, Austria.

Abstract

The gender-specific prevalence of lymphangioleiomyomatosis (LAM) in premenopausal women suggests a hormonal etiology. Despite the antiestrogenic treatment (ovariectomy, tamoxifen) this disease is often refractory to therapy and almost inevitably leads to the patient's death. We describe a case where the antiproliferative effect of systemically applied interferon alpha 2b was successfully employed in addition to ovariectomy and the patient reached complete remission.

PMID:
1471918
[Indexed for MEDLINE]

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