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Neurology. 2004 Jan 13;62(1):132-3.

Antigliadin antibodies in Huntington's disease.

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Department of Neurology, University of Minnesota, Minneapolis, USA.


The relevance of gluten sensitivity in sporadic and hereditary ataxia pathogenesis is unclear. The authors found high antigliadin antibody titers in 23 of 52 (44%) patients with Huntington's disease (HD), suggesting a previously unrecognized association between HD and gluten sensitivity. The results further question "gluten ataxia" as a distinct disease entity and raise the possibility that antigliadin antibodies in ataxia and other neurodegenerative diseases may be an epiphenomenon, the mechanisms of which remain to be investigated.

[Indexed for MEDLINE]

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