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Neurology. 2004 Jan 13;62(1):132-3.

Antigliadin antibodies in Huntington's disease.

Author information

1
Department of Neurology, University of Minnesota, Minneapolis, USA. busha001@umn.edu

Abstract

The relevance of gluten sensitivity in sporadic and hereditary ataxia pathogenesis is unclear. The authors found high antigliadin antibody titers in 23 of 52 (44%) patients with Huntington's disease (HD), suggesting a previously unrecognized association between HD and gluten sensitivity. The results further question "gluten ataxia" as a distinct disease entity and raise the possibility that antigliadin antibodies in ataxia and other neurodegenerative diseases may be an epiphenomenon, the mechanisms of which remain to be investigated.

PMID:
14718716
[Indexed for MEDLINE]

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