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Clin Diagn Lab Immunol. 2004 Jan;11(1):229-34.

Age-related changes in expression of CXCR4 and CCR5 on peripheral blood leukocytes from uninfected infants born to human immunodeficiency virus type 1-infected mothers.

Author information

1
AIDS Virus Research Unit, National Institute for Communicable Diseases, and Department of Virology, Johannesburg, South Africa.

Abstract

Cross-sectional analysis of human immunodeficiency virus-exposed, uninfected infants revealed high proportions of CXCR4-expressing cells in their cord blood, which declined at 4.5 months and increased between 9 and 15 months to levels approaching those of uninfected adults. Proportions of CCR5-expressing cells, however, were very low in cord blood and subsequently increased with age.

PMID:
14715575
PMCID:
PMC321339
DOI:
10.1128/cdli.11.1.229-234.2004
[Indexed for MEDLINE]
Free PMC Article

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