Format

Send to

Choose Destination
Curr Biol. 2004 Jan 6;14(1):R30-2.

Immune activation: death, danger and dendritic cells.

Author information

1
Emory Vaccine Center, 954 Gatewood Road, Atlanta, Georgia 30329, USA. bpulend@rmy.emory.edu

Abstract

Dendritic cells are critical for host immunity, and sense microbes with pathogen recognition receptors. New evidence indicates that these cells also sense uric acid crystals in dead cells, suggesting that the immune system is conscious not only of pathogens, but also of death and danger.

PMID:
14711433
DOI:
10.1016/j.cub.2003.12.020
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center