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Trends Microbiol. 2004 Jan;12(1):1-4.

Transformation and DNA repair: linkage by DNA recombination.

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1
Centre for Molecular Biology and Neuroscience and Institute of Microbiology, University of Oslo, Rikshospitalet, N-0027 Oslo, Norway. tone.tonjum@labmed.uio.no

Abstract

The stability of microbial genomes is constantly challenged by horizontal gene transfer, recombination and DNA damage. Mechanisms for rapid genome variation, adaptation and maintenance are a necessity to ensure microbial fitness and survival in changing environments. Indeed, genome sequences reveal that most, if not all, bacterial species have numerous gene functions for DNA repair and recombination. These important topics were addressed at the Second Genome Maintenance Meeting (GMM2).

PMID:
14700543
[Indexed for MEDLINE]
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