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J Pediatr Surg. 2004 Jan;39(1):31-6.

Patterns of cerebral injury in a series of infants with congenital diaphragmatic hernia utilizing magnetic resonance imaging.

Author information

1
Neonatal Neurology Department, Royal Children's and Women's Hospitals, Murdoch Childrens Research Institute, University of Melbourne, Melbourne, Victoria, Australia.

Abstract

BACKGROUND:

Congenital diaphragmatic hernia (CDH) is a condition with significant mortality and respiratory morbidity. Long-term neurodevelopmental outcome is not yet well documented.

METHODS:

The authors examined all cases of CDH at their institution over a 12-month period and performed magnetic resonance imaging (MRI) of the brain postoperatively.

RESULTS:

Eight of 10 patients survived to have an MR brain scan. All 8 patients had cerebral injury detected on MRI, with a predominance of white matter and deep nuclear gray matter injury.

CONCLUSIONS:

Cerebral injury detected with MRI is common in infants with congenital diaphragmatic hernia. The long-term significance of these MRI abnormalities is unknown, although the need for good long-term neurodevelopmental follow-up of infants with CDH is highlighted.

PMID:
14694367
DOI:
10.1016/j.jpedsurg.2003.09.005
[Indexed for MEDLINE]

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