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Bioinformatics. 2004 Jan 1;20(1):136-7.

TM or not TM: transmembrane protein prediction with low false positive rate using DAS-TMfilter.

Author information

1
Agricultural Biotechnology Center, Szent-Gyorgyi A. 4, Gödöllö, H-2100 Hungary.

Abstract

Web-based servers implementing the DAS-TMfilter algorithm have been launched at three mirror sites and their usage is described. The underlying computer program is an upgraded and modified version of the DAS-prediction method. The new server is (approximately 1 among 100 unrelated queries) while the high efficiency of the original algorithm locating TM segments in queries is preserved (sensitivity of approximately 95% among documented proteins with helical TM regions).

AVAILABILITY:

The server operates at three mirror sites: http://mendel.imp.univie.ac.at/sat/DAS/DAS.html, http://wooster.bip.bham.ac.uk/DAS.html and http://www.enzim.hu/DAS/DAS.html. The program is available on request.

PMID:
14693825
[Indexed for MEDLINE]

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