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J Antibiot (Tokyo). 1992 Nov;45(11):1746-52.

Epoxomicin, a new antitumor agent of microbial origin.

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1
Bristol-Myers Squibb Research Institute, Tokyo, Japan.

Abstract

An actinomycete strain No. Q996-17 produced a novel compound, epoxomicin, which exhibited in vivo antitumor activity against B16 melanoma. Structural studies indicated that it is a new member of the epoxy-beta-aminoketone group, and is closely related to eponemycin.

PMID:
1468981
[Indexed for MEDLINE]
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