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Pediatr Infect Dis J. 2003 Dec;22(12):1101-3.

Vancomycin-resistant Enterococcus faecium endocarditis in a premature infant successfully treated with linezolid.

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Children's Hospital of Michigan, Detroit, USA.


A 4 1/2-month-old, 26-week premature infant with multiple complications of prematurity required a central venous catheter for venous access and antibiotic treatment of bacterial nosocomial infections. He developed tricuspid valve endocarditis with vegetation caused by Enterococcus faecium resistant to ampicillin, vancomycin and quinupristin-dalfopristin but susceptible to linezolid. He was successfully treated with linezolid intravenously (7 weeks) and then orally (2 weeks).

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