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Phys Rev Lett. 2003 Dec 12;91(24):245701. Epub 2003 Dec 9.

Instabilities in complex mixtures with a large number of components.

Author information

1
Department of Physics, University of Surrey, Guildford, Surrey GU2 7XH, United Kingdom. r.sear@surrey.ac.uk

Abstract

Inside living cells are complex mixtures of thousands of components. It is hopeless to try to characterize all the individual interactions in these mixtures. Thus, we develop a statistical approach to approximating them, and examine the conditions under which the mixtures phase separate. The approach approximates the matrix of second-virial coefficients of the mixture by a random matrix, and determines the stability of the mixture from the spectrum of such random matrices.

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