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Rheumatol Int. 2005 Apr;25(3):183-7. Epub 2003 Dec 10.

Reactivation of Epstein-Barr virus in patients with systemic lupus erythematosus.

Author information

1
Division of Immunology, School of Molecular Medical Sciences, University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, UK. mary.huggins@nottingham.ac.uk

Abstract

A link between Epstein-Barr Virus (EBV) and systemic lupus erythematosus (SLE) has been suggested. However, recent advances in molecular technology now permit more detailed analysis. Sera from SLE patients were tested for antibodies to several EBV antigens and had a significantly higher prevalence of immunoglobulin G antibodies against EBV early antigens than in normal or disease controls. This suggests that recent EBV infection or virus reactivation was occurring in these patients.

PMID:
14666378
DOI:
10.1007/s00296-003-0420-2
[Indexed for MEDLINE]

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