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Appl Environ Microbiol. 2003 Dec;69(12):7554-7.

Antifungal 3-hydroxy fatty acids from Lactobacillus plantarum MiLAB 14.

Author information

1
Department of Chemistry, Swedish University of Agricultural Sciences, SE-750 07 Uppsala, Sweden. jorgen.sjogren@kemi.slu.se

Abstract

We report the identification and chemical characterization of four antifungal substances, 3-(R)-hydroxydecanoic acid, 3-hydroxy-5-cis-dodecenoic acid, 3-(R)-hydroxydodecanoic acid and 3-(R)-hydroxytetradecanoic acid, from Lactobacillus plantarum MiLAB 14. The concentrations of the 3-hydroxy fatty acids in the supernatant followed the bacterial growth. Racemic mixtures of the saturated 3-hydroxy fatty acids showed antifungal activity against different molds and yeasts with MICs between 10 and 100 micrograms ml-1.

PMID:
14660414
PMCID:
PMC309954
DOI:
10.1128/aem.69.12.7554-7557.2003
[Indexed for MEDLINE]
Free PMC Article

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