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J Inorg Biochem. 2004 Jan;98(1):161-6.

A formula for correlating pKa values determined in D2O and H2O.

Author information

1
Faculty of Chemistry, University of Wroclaw, Joliot-Curie 14, 50-383 Wroclaw, Poland.

Abstract

A linear correlation between pH-meter readings in equivalent D2O and H2O solutions, determined experimentally, leads to a novel equation, which allows for a direct recalculation of pKa values measured in D2O into a H2O equivalent: pKH=0.929pKH*+0.42. The comparison of this equation with the previously used approach is discussed.

PMID:
14659645
DOI:
10.1016/j.jinorgbio.2003.10.001
[Indexed for MEDLINE]

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