The authors analyze a cohort of 1,831 appendectomy interventions, performed in the years 1996 to 2001 at the Surgery Ward in Prostĕjov. The laparoscopic technique of the intervention was introduced into the ward practice in 1995. The evaluation of patients operated on advanced appendicitis by laparoscopy in 1996 and those operated on in 2001 with a differential approach it became obvious that septic complications were markedly reduced when a differential indication for laparoscopic intervention was applied.