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J Emerg Med. 2003 Nov;25(4):351-6.

Influence of acute resistance exercise on cardiac biomarkers in untrained women.

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Department of Exercise Science, University of Northern Colorado, Greeley, Colorado 80639, USA.


This study was conducted to determine if an initial bout of resistance (weight lifting) exercise by untrained women results in any alterations in indicators of acute myocardial infarction (AMI). Untrained women performed 4 resistance exercises at 70% of their 1 repetition maximum. Blood samples were obtained during the 12 h post-exercise and analyzed for total creatine kinase (CK)-MB, CK-MB subforms 1 and 2, and the relative lymphocyte percentage. Exercise resulted in significant increases in total CK-MB, CK-MB(1), CK-MB(2), and the CK-MB(2)/CK-MB(1) ratio, total leukocyte count, and lymphocyte count. Using several criteria for the assessment of AMI, 22-25% of subjects completing the protocol demonstrated increases in CK-MB(2), CK-MB(2)/CK-MB(1) ratio, and relative lymphocyte percentages that were suggestive of AMI. Thus, our data suggest that moderate resistance exercise can significantly alter blood indicators of AMI, emphasizing the need to determine recent exercise history in patients with possible AMI.

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