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Cell. 2003 Nov 26;115(5):508-10.

Rad53: a controller ensuring the fine-tuning of histone levels.

Author information

1
Institut Curie, Research Section, UMR 218 du CNRS, 75218 Paris cedex 05, France.

Abstract

Checkpoint proteins are activated in response to genotoxic insults or replication stress to maintain genome integrity. Their function is believed to depend largely on the detection of the DNA damage or defects occurring during replication fork progression.

PMID:
14651842
DOI:
10.1016/s0092-8674(03)00931-0
[Indexed for MEDLINE]
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