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Arch Virol. 2003 Dec;148(12):2471-80. Epub 2003 Sep 16.

Cloning and sequencing of Duck circovirus (DuCV).

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P11 Neue Viren/Xenotranplantation, Robert Koch-Institut, Nordufer 20, 13353 Berlin, Germany.


The genome of Duck circovirus (DuCV) is circular and 1996 nts in size. Two major open reading frames were identified, encoding the replicase (V1) and the capsid protein (C1). A stem-loop structure comprising the nonamer 5'-TATTATTAC, conserved in all circo-, nano- and geminiviruses, was found. Unique to DuCV, the region between the 3'-ends of the rep and cap gene contains four repeats of a 44-bp sequence. Phylogenetic analysis shows close relation of DuCV with Goose circovirus and suggests classification of DuCV as a new member of the genus Circovirus of the virus family Circoviridae.

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