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EMBO Rep. 2003 Dec;4(12):1127-31.

Fibulins: physiological and disease perspectives.

Author information

1
Medical University of South Carolina, Department of Cell Biology, 173 Ashley Avenue, Charleston, South Carolina 29425, USA. argraves@musc.edu

Abstract

The fibulins are a family of proteins that are associated with basement membranes and elastic extracellular matrix fibres. This review summarizes findings from studies of animal models of fibulin deficiency, human fibulin gene mutations, human tumours and injury models that have advanced our understanding of the normal and pathological roles of members of this formerly obscure family.

PMID:
14647206
PMCID:
PMC1326425
DOI:
10.1038/sj.embor.7400033
[Indexed for MEDLINE]
Free PMC Article
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