Format

Send to

Choose Destination
See comment in PubMed Commons below
Drug Alcohol Depend. 2003 Dec 11;72(3):265-9.

Is oral fluid analysis as accurate as urinalysis in detecting drug use in a treatment setting?

Author information

1
Addictions Service, Sedman Unit, Dorset HealthCare NHS Trust, 16-18 Tower Road, Bournemouth BH1 4LP, UK. gerals.bennett@dorsethc-tr.swest.nhs.uk

Abstract

BACKGROUND:

Technology for testing oral fluid (OF) for the presence of drugs is available for treatment services and is more attractive than urinalysis: its validity is not well established.

AIMS:

Compare the accuracy of methods of on-site testing of OF and urine.

DESIGN:

Comparison of the sensitivity and specificity of on-site testing of samples of OF and urine collected on the same occasion, using subsequent blind laboratory analysis of the same urine samples as the standard.

SETTING:

British addiction treatment service.

PARTICIPANTS:

157 drug dependent persons, 89% with evidence of opiates, 73% male, and 85% aged between 20 and 35 years.

MEASUREMENTS:

Assessment of presence of four drugs using SYVA ETS urinalysis and Cozart Rapiscan OF Drug Test systems. Laboratory urinalysis using microplate enzyme-immunoassay technique.

RESULTS:

The sensitivity of OF tests and urinalysis were, respectively, for opiates 91 and 91%, methadone 91 and 94%, and benzodiazepines 6 and 72%. The specificity of OF tests and urinalysis were, respectively, for opiates 78 and 67%, methadone 90 and 95%, and benzodiazepines 95 and 96%. Amphetamine usage was rare.

CONCLUSIONS:

OF testing is as accurate as urinalysis in detecting the presence of opiates and methadone, and the absence of methadone and benzodiazepines.

PMID:
14643943
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center