Medical resource use and costs among rheumatoid arthritis patients receiving disease-modifying antirheumatic drug therapy

Arthritis Care Res. 2000 Aug;13(4):213-26. doi: 10.1002/1529-0131(200008)13:4<213::aid-anr6>3.0.co;2-2.

Abstract

Objective: To identify costs among rheumatoid arthritis (RA) patients receiving alternative disease-modifying antirheumatic drug (DMARD) therapies.

Methods: Using managed care organization data, we identified members who (a) were prescribed any DMARD therapy for two consecutive months between July 1993 and February 1998, (b) were aged > or = 18 years, (c) had > or = 6 months of DMARD-free enrollment prior to the first DMARD, and (d) had a diagnosis of RA.

Results: The average age of the cohort (n = 571) was 51 years, and 70% were women. Mean duration of enrollment following initiation of DMARD therapy (observation period) was 19.5 months; 28.8% of patients switched DMARD regimens. The average monthly cost of care was $853, of which $294 (34%) was for RA-coded medical services. Monthly RA-coded costs varied by DMARD: hydroxychloroquine $227 (n = 252), methotrexate $340 (n = 185); sulfasalazine $233 (n = 49), and other mono/combination therapy $425 (n = 85) (P = 0.001).

Conclusion: Costs of RA-coded care in patients receiving DMARDs are low and vary by DMARD.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antirheumatic Agents / economics
  • Antirheumatic Agents / therapeutic use*
  • Arthritis, Rheumatoid / drug therapy*
  • Arthritis, Rheumatoid / economics*
  • Direct Service Costs / statistics & numerical data
  • Drug Costs
  • Drug Therapy, Combination
  • Female
  • Health Care Costs / statistics & numerical data
  • Health Resources / economics*
  • Health Resources / statistics & numerical data*
  • Health Services Research
  • Humans
  • Hydroxychloroquine / therapeutic use
  • Male
  • Managed Care Programs / economics
  • Managed Care Programs / statistics & numerical data
  • Methotrexate / therapeutic use
  • Middle Aged
  • Midwestern United States
  • New England
  • Sulfasalazine / therapeutic use
  • Time Factors
  • Treatment Outcome

Substances

  • Antirheumatic Agents
  • Sulfasalazine
  • Hydroxychloroquine
  • Methotrexate