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Am J Obstet Gynecol. 2003 Nov;189(5):1383-8.

Screening for gestational diabetes mellitus by a model based on risk indicators: a prospective study.

Author information

1
Department of Endocrinology, Odense University Hospital, Kløvervaenget 6, DL-5000 Odense, Denmark. DorteMJ@dadlnet.dk

Abstract

OBJECTIVE:

This study was performed to prospectively evaluate a screening model for gestational diabetes mellitus on the basis of clinical risk indicators.

STUDY DESIGN:

In a prospective multicenter study with 5235 consecutive pregnant women, diagnostic testing with a 2-hour 75-g oral glucose tolerance test was routinely performed in women with risk indicators and offered to women without risk indicators as part of the study.

RESULTS:

Forty-four percent of the women underwent testing, 43% declined participation, 6% did not speak Danish, and 7% could not be contacted. By extrapolation of the results from tested women to the whole group in question, a 2.4% prevalence of gestational diabetes mellitus was calculated. Sensitivity and specificity of the model was 80.6 (73.7-87.6) and 64.8 (63.5-66.1), respectively (95% CIs).

CONCLUSION:

Under ideal conditions, sensitivity of the model was comparable with universal screening by fasting glucose or a 1-hour 50-g glucose challenge test. Both screening and diagnostic testing could be avoided in two thirds of all pregnant women.

PMID:
14634573
DOI:
10.1067/s0002-9378(03)00601-x
[Indexed for MEDLINE]

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