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Int J Psychophysiol. 2003 Dec;51(1):5-15.

Changes in auditory cortex and the development of mismatch negativity between 2 and 6 months of age.

Author information

1
Department of Psychology, McMaster University, Hamilton, Canada ON L8S 4B2. ljt@mcmaster.ca

Abstract

Evoked responses to stimulus deviance were compared in infants between 2 and 6 months of age. A deviant stimulus containing a short silent gap occasionally replaced a repeating standard stimulus matched in duration, intensity and approximate spectral content. At two months, the standard stimuli evoked only a positive slow wave, and its amplitude was increased in response to the deviant stimuli. By 6 months, the deviant stimuli evoked an increased negativity at approximately 200 ms, similar to the mismatch negativity (MMN) response in adults. The results are considered with respect to layer-specific cortical maturation during this period.

PMID:
14629918
[Indexed for MEDLINE]

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