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Oral Dis. 2003 Sep;9(5):269-72.

Oral involvement in a case of AA amyloidosis.

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  • 1Department of Oral Medicine/Pathology, Dental School of Aristotle University of Thessaloniki, Thessaloniki, Greece.


A case of oral involvement of amyloid associated (AA) amyloidosis (secondary systemic amyloidosis) in a patient who is suffering from psoriatic arthritis and ankylosing spondylitis, is described. The patient was complaining of pain in the oral cavity (burning mouth), especially on the tongue, and difficulty in chewing and swallowing foods. Oral examination revealed a few papules on the dorsum of the tongue associated with xerostomia. In addition, two slightly painful, small ulcers, localized on the vestibule of the mouth were observed. Biopsy of the tongue demonstrated amyloid deposits.

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