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Microbes Infect. 2003 Nov;5(13):1249-53.

Association of Chlamydia pneumoniae with central nervous system disease.

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Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, USA.


Chlamydia pneumoniae is a common respiratory pathogen that is now being incriminated in a number of chronic diseases. The ability of C. pneumoniae to infect and persist in macrophages makes it a likely candidate to disseminate in a number of different tissues, including those of the central nervous system. This review addresses the potential and the underlying mechanisms by which C. pneumoniae infections can play a role in such diverse neurological diseases as multiple sclerosis and Alzheimer's disease.

[Indexed for MEDLINE]

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