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Traffic. 2003 Nov;4(11):717-23.

Function of caveolae in Ca2+ entry and Ca2+-dependent signal transduction.

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1
Department of Nephrology and Endocrinology, University of Tokyo, Tokyo 113-8655, Japan.

Abstract

The correct spatial and temporal control of Ca2+ signaling is essential for such cellular activities as fertilization, secretion, motility, and cell division. There has been a long-standing interest in the role of caveolae in regulating intracellular Ca2+ concentration. In this review we provide an updated view of how caveolae may regulate both Ca2+ entry into cells and Ca2+-dependent signal transduction

PMID:
14617355
[Indexed for MEDLINE]
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