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Microbes Infect. 2003 Nov;5(14):1299-306.

Phagocytosis by neutrophils.

Author information

1
Cell Biology Program, Hospital for Sick Children and Department of Biochemistry, University of Toronto, Toronto, ON, Canada M5G 1X8.

Abstract

Phagocytosis is central to the microbicidal function of neutrophils. Pathogens are initially engulfed into a plasma membrane-derived vacuole, the phagosome, which proceeds to acquire degradative properties by a complex process termed maturation. In this chapter, we discuss the current knowledge of the molecular mechanisms underlying phagosome formation and maturation in neutrophils.

PMID:
14613773
DOI:
10.1016/j.micinf.2003.09.014
[Indexed for MEDLINE]

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