Send to

Choose Destination
See comment in PubMed Commons below
Biomacromolecules. 2003 Nov-Dec;4(6):1466-86.

Recent developments in ring opening polymerization of lactones for biomedical applications.

Author information

  • 1Department of Fibre and Polymer Technology, The Royal Institute of Technology, S-10044 Stockholm, Sweden.


Aliphatic polyesters prepared by ring-opening polymerization of lactones are now used worldwide as bioresorbable devices in surgery (orthopaedic devices, sutures, stents, tissue engineering, and adhesion barriers) and in pharmacology (control drug delivery). This review presents the various methods of the synthesis of polyesters and tailoring the properties by proper control of molecular weight, composition, and architecture so as to meet the stringent requirements of devices in the medical field. The effect of structure on properties and degradation has been discussed. The applications of these polymers in the biomedical field are described in detail.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Chemical Society
    Loading ...
    Write to the Help Desk