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Eur J Clin Microbiol Infect Dis. 2003 Dec;22(12):746-8. Epub 2003 Nov 6.

Emergence of a teicoplanin-resistant small colony variant of Staphylococcus epidermidis during vancomycin therapy.

Author information

1
Bacteriology Laboratory, University of Basel Hospitals and Clinics, Petersgraben 4, 4031 Basel, Switzerland. hadler@uhbs.ch

Abstract

Small colony variants of Staphylococcus aureus can cause persistent and recurrent infections. There are only a few reports of small colony variants of coagulase-negative staphylococci. Herein a case of infection with a teicoplanin-resistant small colony variant of Staphylococcus epidermidis is presented. The small colony variant was isolated from blood cultures of a patient with acute leukaemia and therapy-induced neutropenia who was treated with vancomycin for catheter-associated bloodstream infection. Despite removal of the catheter and adequate antibiotic therapy, the infection did not clear and the patient died 20 days after continuous antibiotic therapy.

PMID:
14605939
DOI:
10.1007/s10096-003-1029-9
[Indexed for MEDLINE]

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