This study assessed immunological changes in apparently healthy children under a slight (less than the sanitary standards) urban pollution with heavy metals (Co, Pb, Cr, Cd, Mn, Ni, Zn, and Cu). Their pollution of the urban environment was determined with the contamination of snow cover and ambient air in Kazan. With low levels of ambient air pollution with heavy metals, monitoring the level of environmental pollution is an adequate method for evaluating the urban area, which allows the latter to be ranged by the degree of pollution. Apparently healthy children who live under relatively good environmental conditions are at risk for allergic and autoimmune diseases or secondary immunological somatic pathology.